Sometimes the upper gum (alveolus) can also be affected. The chance of developing a cleft increases if other family members are affected.Ī cleft lip is an abnormal gap or opening in the upper lip.Some factors that may increase a child’s chance of being born with a cleft lip or palate include smoking, alcohol consumption or some medications taken during pregnancy.The exact cause of cleft lip and palate is unclear, however it is thought that both genetic and environmental factors may contribute.A small percentage of affected infants may have abnormalities elsewhere in the face or in other parts of their bodies. Approximately 70% of infants with cleft lip and palate and 50% of infants with cleft palate only are non-syndromic.Cleft lip, cleft palate and cleft lip and palate are among the most common congenital deformities and affect 1.1 in 1000 infants.Incidence and risk factors for cleft lip and palate A thorough examination of a baby’s face and mouth at birth is required to diagnose the type and severity of cleft. 1 Diagnosis of cleft lip and palateĪ cleft lip is often detected on ultrasound at 20 weeks gestation, however a cleft palate can be more difficult to detect at this time. The cleft may extend through to involve the lip as well. In some cases, however, the roof of the mouth does not fuse together properly, creating a cleft palate. During this time, the roof of the mouth begins developing and eventually the two sides of the palate unite evenly in most infants. The lip and palate begin forming during just the first few weeks of gestation, often before a woman even knows she is pregnant.
We recommend that you also refer to more contemporaneous evidence in the interim. Please note that all guidance is currently under review and some may be out of date.
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